Pioneering Cardiac Arrhythmia Research: Modeling, Innovation, and Precision Therapy.
The Ranjan Lab integrates cardiac computational modeling, advanced imaging, and human clinical data to understand atrial fibrillation and other cardiac arrhythmias — and to guide personalized ablation therapy.
Revolutionizing Heart Health:
Advancing Understanding and Therapy of Cardiac Arrhythmias
The Ranjan Lab studies tissue- and organ-scale physiology and pathophysiology in cardiac arrhythmias — atrial fibrillation, atypical left atrial flutter, and ventricular tachycardia — integrating cardiac computational modeling, machine learning, preclinical experimental models, cardiac magnetic resonance imaging, biochemical assays, electrophysiological mapping, and human clinical data to discover novel therapeutic targets.
About Ranjan LabOur Research
The Ranjan Laboratory studies tissue- and organ-scale physiology and pathophysiology in cardiac arrhythmias, integrating cardiac computational modeling, machine learning, preclinical experimental models, cardiac magnetic resonance imaging, biochemical assays, electrophysiological mapping, and human clinical data. His group uses personalized computational models to deliver optimal ablation lesions.
Featured Publications
Recent publications from the Ranjan Lab advancing the understanding and treatment of cardiac arrhythmias.
Diffuse functional and structural abnormalities in fibrosis: Potential structural basis for sustaining atrial fibrillation — Kwan E et al., Heart Rhythm. 2025;22:1820-1828.
Functional and Structural Remodeling as Atrial Fibrillation Progresses in a Persistent Atrial Fibrillation Canine Model — Kwan E et al., JACC: Clinical Electrophysiology. 2025;11(4):720-734.
Are drivers recurring or ephemeral? Observations from serial mapping of persistent atrial fibrillation — Hunt B et al., Europace. 2024;26(11):euae269.
Area Available for Atrial Fibrillation to Propagate Is an Important Determinant of Recurrence After Ablation — Kamali R et al., JACC: Clinical Electrophysiology. 2021;7(7):896-908.
Mentorship and Training
Dr. Ranjan is listed as a faculty mentor with the University of Utah Office of Undergraduate Research.
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